Two-color quark matter: U(1)_A restoration, superfluidity, and quarkyonic phase

We discuss the phase structure of quantum chromodynamics (QCD) with two colors and two flavors of light quarks. This is motivated by the increasing interest in the QCD phase diagram as follows: (1) The QCD critical point search has been under intensive dispute and its location and existence suffer from uncertainty of effective U(1)_A symmetry restoration. (2) A new phase called quarkyonic matter is drawing theoretical and experimental attention but it is not clear whether it can coexist with diquark condensation. We point out that two-color QCD is nontrivial enough to contain essential ingredients for (1) and (2) both, and most importantly, is a system without the sign problem in numerical simulations on the lattice. We adopt the two-flavor Nambu-Jona-Lasinio model extended with the two-color Polyakov loop and make quantitative predictions which can be tested by lattice simulations.Comment: 14 pages, REVTeX4, 12 eps figures; v2: version published in Phys. Rev. D; v3: an error in the Appendix fixed, Fig. 9 modified accordingl

Spontaneous symmetry breaking in the linear sigma model at finite chemical potential: One-loop corrections

We investigate spontaneous symmetry breaking within the linear sigma model with the SU(2)xU(1) internal symmetry at finite chemical potential, which was suggested as a model for kaon condensation in the CFL phase of dense quark matter. One-loop corrections to the scalar field effective potential as well as its propagator are calculated. Particular attention is paid to the type-II Goldstone boson that appears in the Bose--Einstein condensed phase. Furthermore, we show that the type-I Goldstone boson -- the superfluid phonon -- is allowed to decay due to the nonlinearity of its dispersion relation at high momentum, and determine its decay width.Comment: 13 pages, REVTeX4, 37 eps figures; v2: substantial error in Sec. IV corrected, references added, other minor corrections; version to appear in Phys. Rev.

Aesthetic satisfaction in lip and palate clefts: a comparative study between secondary and tertiary bone grafting

Lip and palate cleft represent one of the most frequently occurring congenital deformity, which includes dental anomalies, such as variation in tooth number and position. In case of hypodontia implant-prosthetic rehabilitation offers significant advantages in terms of function, aesthetics and quality of life and bone graft is usually needed. Secondary bone grafting, generally performed in the mixed dentition phase (years 8-11) seems to be the most successful method to allow for rehabilitation. It's often necessary to perform a tertiary bone grafting in adult age in order to achieve better bone quantity and quality before implant placement. Aim of this retrospective study was to evaluate the aesthetic perception that patients had of themselves comparing dental implants placed in tertiary grafted alveolar cleft sites with a previous secondary grafting to only secondary grafting. Between 2009 and 2012, fourteen alveolar cleft were treated with implant rehabilitation and eleven of them received tertiary bone grafting six months prior to implant placement. All patients were questioned to give a score from 1 to 10 their aesthetic satisfaction of their smile before and after implant rehabilitation and during pre-surgery provisional rehabilitation. At the end of their prosthesis rehabilitation patients who received tertiary bone grafting resulted more satisfied than those who had secondary bone grafting only (9.5 vs 8)

Gingival hyperplasia around dental implants in jaws reconstructed with free vascularized flaps: a case report series

Free vascularized flaps are the gold standard for reconstruction of the facial skeleton after surgical ablation of pathologies or when important atrophy of the jaws exists. A frequent problem seen during prosthetic rehabilitation after reconstruction with free vascularized flaps is the onset of hyperplastic granulomatous reactive tissue around the prosthetic abutment of the implant. The features of this phenomenon seem to be directly related to the characteristics of the periimplant tissue and of the manufacturing materials of the prosthesis and abutments. This complication can be seen quite often; we found it in 7 of 40 patients (17.5%). It does not seem to significantly affect the survival rate of implants. The aim of the study was to analyze the behavior of such lesions and to suggest our clinical approach with the management of these kinds of patients and complications. To remove gingival hyperplasia, we used either a traditional cold scalpel or an electric cautery or laser. We had good results using these tools. The onset of this phenomenon was not influenced by either the kind of implant and free flaps used or by the local conditions of the patients (such as radiotherapy). The number of recurrences was highly influenced by the oral hygiene of the patients

Histological and immunohistochemical evaluation of mandibular bone tissue regeneration

The purpose of the study was to perform an immunohistochemical and histological evaluation of samples taken from different bone regeneration procedures in atrophic human mandible. 30 patients (15 men and 15 women, age range of 35-60 years), non-smokers, with good general and oral health were recruited in this study and divided into three groups. The first group included patients who were treated with blood Concentration Growth Factors (bCGF), the second group included patients who were treated with a mixture of bCGF and autologous bone, while the third group of patients was treated with bCGF and tricalcium phosphate/hydroxyapatite (TCP-HA). Six months after the regenerative procedures, all patients undergone implant surgery, and a bone biopsy was carried out in the site of implant insertion. Each sample was histologically and immunohistochemically examined. Histological evaluation showed a complete bone formation for group II, partial ossification for group I, and moderate ossification for group III. Immunohistochemical analysis demonstrated a statistically significant difference between the three groups, and the best clinical result was obtained with a mixture of bCGF and autologous bone

Spontaneous breaking of continuous translational invariance

Unbroken continuous translational invariance is often taken as a basic assumption in discussions of spontaneous symmetry breaking (SSB), which singles out SSB of translational invariance itself as an exceptional case. We present a framework which allows us to treat translational invariance on the same footing as other symmetries. It is shown that existing theorems on SSB can be straightforwardly extended to this general case. As a concrete application, we analyze the Nambu-Goldstone modes in a (ferromagnetic) supersolid. We prove on the ground of the general theorems that the Bogoliubov mode stemming from a spontaneously broken internal U(1) symmetry and the longitudinal phonon due to a crystalline order are distinct physical modes.Comment: 14 pages, 4 pdf/jpg figures, REVTeX 4.1; v2: section IV expanded, new appendix and references added, numerous other minor modifications throughout the tex

Monolithic zirconia and digital impression: case report

The aim of this study is to present a clinical case of a full arch prosthetic rehabilitation on natural teeth, combining both digital work-flow and monolithic zirconi

Erratum: Identification of responsive cells in the developing somite supports a role for β‐catenin‐dependent Wnt signaling in maintaining the DML myogenic progenitor pool

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90355/1/23720_ftp.pd

Impact of Cage Size and Enrichment (Tube and Shelf) on Heart Rate Variability in Rats

Rats respond physiologically and behaviorally to environmental stressors. As cage conditions can be a stressor, it is important that experimental results acquired from caged rats are not confounded by these responses. This study determined the effects of cage size and cage enrichment (tube and shelf) on heart rate variability (HRV) in rats as a measure of stress. Electrocardiogram data were collected from 5 male Sprague-Dawley rats, each implanted with a radio-telemetric transducer to assess the ratio of the low to high frequency components of the HRV power spectrum (LF/HF). This ratio reflects the degree of sympathetic versus parasympathetic nervous activity and increases with decreasing HRV. Rats were housed for 3 weeks in each of the following cage conditions: small un-enriched, small enriched, large un-enriched and large enriched. Cage enrichment and/or larger cages did not significantly alter LF/HF values compared to the small, un-enriched cage condition, when considered independent of the sleep/wake cycle. However, when results were pooled for all cage conditions, LF/HF significantly increased during the wake cycle compared to the sleep cycle. Further analysis showed that this difference was only statistically significant for the un-enriched cage condition. Thus the presence of a tube and a shelf in a rodent cage can alter the diurnal rhythm of HRV in rats and this should be taken into account when designing experiments in which HRV is an outcome

Defense Mechanisms of Hepatocytes Against Burkholderia pseudomallei

The Gram-negative facultative intracellular rod Burkholderia pseudomallei causes melioidosis, an infectious disease with a wide range of clinical presentations. Among the observed visceral abscesses, the liver is commonly affected. However, neither this organotropism of B. pseudomallei nor local hepatic defense mechanisms have been thoroughly investigated so far. Own previous studies using electron microscopy of the murine liver after systemic infection of mice indicated that hepatocytes might be capable of killing B. pseudomallei. Therefore, the aim of this study was to further elucidate the interaction of B. pseudomallei with these cells and to analyze the role of hepatocytes in anti-B. pseudomallei host defense. In vitro studies using the human hepatocyte cell line HepG2 revealed that B. pseudomallei can invade these cells. Subsequently, B. pseudomallei is able to escape from the vacuole, to replicate within the cytosol of HepG2 cells involving its type 3 and type 6 secretion systems, and to induce actin tail formation. Furthermore, stimulation of HepG2 cells showed that IFNγ can restrict growth of B. pseudomallei in the early and late phase of infection whereas the combination of IFNγ, IL-1β, and TNFα is required for the maximal antibacterial activity. This anti-B. pseudomallei defense of HepG2 cells did not seem to be mediated by inducible nitric oxide synthase-derived nitric oxide or NADPH oxidase-derived superoxide. In summary, this is the first study describing B. pseudomallei intracellular life cycle characteristics in hepatocytes and showing that IFNγ-mediated, but nitric oxide- and reactive oxygen species-independent, effector mechanisms are important in anti-B. pseudomallei host defense of hepatocytes